Article
Visual Detection of Multiplex MicroRNAs Using Cationic Conjugated Polymer Materials.
ACS applied materials & interfaces - 20 Jan 2016
Zhou Yuanyuan, Zhang Jiangyan, Zhao Likun, Li Yingcun, Chen Hui, Li Shengliang, Cheng Yongqiang
Abstract excerpt
A simple, visual, and specific method for simultaneous detection of multiplex microRNAs (miRNAs) has been developed by integrating duplex-specific nuclease (DSN)-induced amplification with cationic conjugated polymer (CCP) materials. The probe DNA with a complementary sequence to target miRNA is labeled with fluorescein dye (FAM). Without target miRNA, the single-strand DNA probe cannot be digested by DSN. Upon...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
