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Article

Single-nucleotide polymorphism (SNP) genotyping using cationic conjugated polymers in homogeneous solution.

Nature protocols - 1 Jan 2009

Duan Xinrui, Yue Wei, Liu Libing, Li Zhengping, Li Yuliang, He Fuchu, Zhu Daoben, Zhou Gangqiao, Wang Shu

Abstract excerpt

This protocol describes a simple, convenient and sensitive single-nucleotide polymorphism (SNP) genotyping method using an optically amplifying cationic conjugated polymer and single base primer extension reaction. The fluorescence resonance energy transfer (FRET) efficiency between the conjugated polymer (PFP, poly{(1,4-phenylene)-2,7-[9,9-bis(6'-N,N,N-trimethyl ammonium)-hexyl fluorene] dibromide}) and a...

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Source

Identifiers

PMID: 19498378
DOI: 10.1038/nprot.2009.70

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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