Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Fluorescence and visual detection of single nucleotide polymorphism using cationic conjugated polyelectrolyte.

Langmuir : the ACS journal of surfaces and colloids - 10 Jan 2012

Wang Yifan, Zhan Ruoyu, Li Tianhu, Pu Kan-Yi, Wang Yanyan, Tan Yoke Cheng, Liu Bin

Abstract excerpt

We report a simple assay for visual detection of single nucleotide polymorphisms (SNPs) with good sensitivity and selectivity. The selectivity is determined by Escherichia coli (E. coli) DNA ligase mediated circular formation upon recognition of the point mutation on DNA targets. Rolling cycle amplification (RCA) of the perfect-matched DNA target is then initiated using the in situ formed circular template in the...

Topics

Join the communities discussing this publication.

Cations
Electrolytes
Polymorphism, Single Nucleotide
Spectrometry, Fluorescence

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 22047010
DOI: 10.1021/la203714e

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Fluorescence and visual detection of single nucleotide polymorphism using cationic conjugated polyelectrolyte.PMID 22047010Read ↗

Conjugated polyelectrolyte-DNA complexes for multi-color and one-tube SNP genotyping assays.Semantic proximity Read ↗

Conjugated polyelectrolyte amplified thiazole orange emission for label free sequence specific DNA detection with single nucleotide polymorphism selectivity.Semantic proximity Read ↗

Homogeneous and one-step fluorescent allele-specific PCR for SNP genotyping assays using conjugated polyelectrolytes.Semantic proximity Read ↗

Single-nucleotide polymorphism (SNP) genotyping using cationic conjugated polymers in homogeneous solution.Semantic proximity Read ↗

Cationic conjugated polymers for optical detection of DNA methylation, lesions, and single nucleotide polymorphisms.Semantic proximity Read ↗

A simple and ultrasensitive fluorescence assay for single-nucleotide polymorphism.Semantic proximity Read ↗

Fluorescent detection of single nucleotide polymorphism utilizing a hairpin DNA containing a nucleotide base analog pyrrolo-deoxycytidine as a fluorescent probe.Semantic proximity Read ↗

Novel biosensing methodologies for improving the detection of single nucleotide polymorphism.Semantic proximity Read ↗

A sensitive and homogeneous SNP detection using cationic conjugated polymers.Semantic proximity Read ↗

Rolling circle amplification combined with gold nanoparticle aggregates for highly sensitive identification of single-nucleotide polymorphisms.Semantic proximity Read ↗

Homogeneous and label-free fluorescence detection of single-nucleotide polymorphism using target-primed branched rolling circle amplification.Semantic proximity Read ↗

Advanced Ligase Chain Reaction Strategy to Generate a Circular DNA Walker for Electrochemiluminescent Detection of Single Nucleotide Polymorphism.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.