Article

CRISPR/Cas13a-triggered entropy-driven amplification for colorimetric and fluorescent dual-mode detection of microRNA

2023-11-09

Abstract excerpt

<title>Abstract</title> <p>MicroRNAs (miRNAs) are crucial biomarkers for the early detection and monitoring of disease progression of chronic obstructive pulmonary disease (COPD). Herein, we have devised a method for detecting miRNA using a combination of colorimetric and graphene oxide-based fluorescent techniques. The target miRNA in our design could precisely activate the <italic>trans</italic>-cleavage activi...

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Literature Corpus work: 13cb0d27-e058-5b5e-a4c9-2f94b1532e68
DOI: 10.21203/rs.3.rs-3505086/v1

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