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Article

Exponential amplification reaction and triplex DNA mediated aggregation of gold nanoparticles for sensitive colorimetric detection of microRNA.

Analytica chimica acta - 25 Jan 2020

Wei Shuangqin, Chen Guifang, Jia Xingqing, Mao Xinyue, Chen Tianshu, Mao Dongsheng, Zhang Wenju, Xiong Wujun

Abstract excerpt

Abnormal expression of specific microRNAs (miRNAs) is associated with the occurrence, development and prognosis of many diseases. In this study, a miRNA detection method based on exponential amplification reaction (EXPAR) and triplex DNA mediated aggregation of gold nanoparticles (AuNPs) was established. Specifically, one class of AuNPs is conjugated with an EXPAR probe, on which there is a complementary sequence...

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Identifiers

PMID: 31864620
DOI: 10.1016/j.aca.2019.10.020

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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