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Ru(bpy)32+ Incorporated Luminescent Polymer Dots: Double-Enhanced Electrochemiluminescence for Detection of Single-Nucleotide Polymorphism.

Analytical chemistry - 18 Jul 2017

Feng Yaqiang, Sun Feng, Wang Ningning, Lei Jianping, Ju Huangxian

Abstract excerpt

Encapsulating a large amount of electrochemiluminescence (ECL) active molecules into one nanoparticle for single-target recognition can greatly improve the sensitivity of the ECL assay. This work used luminescent conjugated polymer as a carrier to synthesize Ru(bpy)32+-doped polymer dots (RuPdots). The RuPdots with an average size of 20 nm and encapsulation of about 1354 Ru(bpy)32+ showed greatly enhanced ECL...

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PMID: 28640589
DOI: 10.1021/acs.analchem.7b01603

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KRAS

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