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Article

Regional heritability mapping method helps explain missing heritability of blood lipid traits in isolated populations.

Heredity - 1 Mar 2016

Shirali M, Pong-Wong R, Navarro P, Knott S, Hayward C, Vitart V, Rudan I, Campbell H, Hastie N D, Wright A F, Haley C S

Abstract excerpt

Single single-nucleotide polymorphism (SNP) genome-wide association studies (SSGWAS) may fail to identify loci with modest effects on a trait. The recently developed regional heritability mapping (RHM) method can potentially identify such loci. In this study, RHM was compared with the SSGWAS for blood lipid traits (high-density lipoprotein (HDL), low-density lipoprotein (LDL), plasma concentrations of total...

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Identifiers

PMID: 26696135
DOI: 10.1038/hdy.2015.107
PMCID: PMC4751621

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TG

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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