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Article

A method to estimate the contribution of regional genetic associations to complex traits from summary association statistics.

Scientific reports - 8 Jun 2016

Pare Guillaume, Mao Shihong, Deng Wei Q

Abstract excerpt

Despite considerable efforts, known genetic associations only explain a small fraction of predicted heritability. Regional associations combine information from multiple contiguous genetic variants and can improve variance explained at established association loci. However, regional associations are not easily amenable to estimation using summary association statistics because of sensitivity to linkage...

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Identifiers

PMID: 27273519
DOI: 10.1038/srep27644
PMCID: PMC4897708

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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