Article
Genetic contribution of SCARB1 variants to lipid traits in African Blacks: a candidate gene association study.
BMC medical genetics - 12 Nov 2015
Niemsiri Vipavee, Wang Xingbin, Pirim Dilek, Radwan Zaheda H, Bunker Clareann H, Barmada M Michael, Kamboh M Ilyas, Demirci F Yesim
Abstract excerpt
BACKGROUND: High-density lipoprotein cholesterol (HDL-C) exerts many anti-atherogenic properties including its role in reverse cholesterol transport (RCT). Scavenger receptor class B member 1 (SCARB1) plays a key role in RCT by selective uptake of HDL cholesteryl esters. We aimed to explore the genetic contribution of SCARB1 to affecting lipid levels in African Blacks from Nigeria. METHODS: We resequenced 13...
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