Article

SNP and Haplotype Regional Heritability Mapping (SNHap-RHM): joint mapping of common and rare variation affecting complex traits

2021-08-04

Abstract excerpt

We describe a genome-wide analytical approach, SNP and Haplotype Regional Heritability Mapping (SNHap-RHM), that provides regional estimates of the heritability across locally defined regions in the genome. This approach utilises relationship matrices that are based on sharing of SNP and haplotype alleles at local haplotype blocks delimited by recombination boundaries in the genome. We implemented the approach on...

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Literature Corpus work: 5f5f083a-f832-59ee-92bf-f08daf3fea91
DOI: 10.1101/2021.08.02.454788

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