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Article

Fibroblast Growth Factor Receptors: From the Oncogenic Pathway to Targeted Therapy.

Current molecular medicine - 1 Jan 2016

Saichaemchan S, Ariyawutyakorn W, Varella-Garcia M

Abstract excerpt

The family of fibroblast growth factor (FGFs) and their receptors (FGFRs) regulates vital roles in many biological processes affecting cell proliferation, migration, differentiation and survival. Deregulation of the FGF/FGFR signaling pathway in cancers has been better understood and the main molecular mechanisms responsible for the activation of this pathway are gene mutations, gene fusions and gene...

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Source

Identifiers

PMID: 26695695
DOI: 10.2174/1566524016666151222144231

Genes

FGFR1
FGFR2
FGFR3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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