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Article

Fibroblast growth factors and their receptors in cancer.

The Biochemical journal - 15 Jul 2011

Wesche Jørgen, Haglund Kaisa, Haugsten Ellen Margrethe

Abstract excerpt

FGFs (fibroblast growth factors) and their receptors (FGFRs) play essential roles in tightly regulating cell proliferation, survival, migration and differentiation during development and adult life. Deregulation of FGFR signalling, on the other hand, has been associated with many developmental syndromes, and with human cancer. In cancer, FGFRs have been found to become overactivated by several mechanisms,...

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Identifiers

PMID: 21711248
DOI: 10.1042/BJ20101603

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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