Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Future applications of FGF/FGFR inhibitors in cancer.

Expert review of anticancer therapy - 1 Sept 2018

Ghedini Gaia Cristina, Ronca Roberto, Presta Marco, Giacomini Arianna

Abstract excerpt

INTRODUCTION: Deregulation of the fibroblast growth factor (FGF)/FGF receptor (FGFR) network occurs frequently in tumors due to gene amplification, activating mutations, and oncogenic fusions. Thus, the development of FGF/FGFR-targeting therapies is the focus of several basic, preclinical, and clinical studies. Areas covered: This review will recapitulate the status of current FGF/FGFR-targeted drugs. Expert...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antineoplastic Agents
Share to Biomarkers, Tumor
Share to Drug Development

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance, Neoplasm

Share to Fibroblast Growth Factors

Share to Gene Amplification

Share to Molecular Targeted Therapy

Share to Receptors, Fibroblast Growth Factor

Source

Identifiers

PMID: 29936878
DOI: 10.1080/14737140.2018.1491795

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Future applications of FGF/FGFR inhibitors in cancer.PMID 29936878Read ↗

FGFR a promising druggable target in cancer: Molecular biology and new drugs.Semantic proximity Read ↗

Selective FGFR/FGF pathway inhibitors: inhibition strategies, clinical activities, resistance mutations, and future directions.Semantic proximity Read ↗

Fibroblast Growth Factor Receptors: From the Oncogenic Pathway to Targeted Therapy.Semantic proximity Read ↗

FGFR families: biological functions and therapeutic interventions in tumorsSemantic proximity Read ↗

Fibroblast growth factors and their receptors in cancer.Semantic proximity Read ↗

Molecular Targeting of the Fibroblast Growth Factor Receptor (FGFR) Pathway Across Various CancersSemantic proximity Read ↗

Landscape of FGF/FGFR Alterations in 12,372 Chinese Cancer PatientsSemantic proximity Read ↗

Fibroblast growth factor receptor signaling in hereditary and neoplastic disease: biologic and clinical implications.Semantic proximity Read ↗

Inhibition of FGF-FGFR and VEGF-VEGFR signalling in cancer treatment.Semantic proximity Read ↗

Novel Regulatory Factors and Small-Molecule Inhibitors of FGFR4 in CancerSemantic proximity Read ↗

Role of fibroblast growth factor receptor 4 in cancer.Semantic proximity Read ↗

FGFR-TKI resistance in cancer: current status and perspectives.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.