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Article

Aberrant Splicing of Estrogen Receptor, HER2, and CD44 Genes in Breast Cancer

1 Jan 2015

Abstract excerpt

Breast cancer (BC) is the most common cause of cancer-related death among women under the age of 50 years. Established biomarkers, such as hormone receptors (estrogen receptor [ER]/progesterone receptor) and human epidermal growth factor receptor 2 (HER2), play significant roles in the selection of patients for endocrine and trastuzumab therapies. However, the initial treatment response is often followed by tumor...

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PMID: 26692764
DOI: 10.4137/geg.s35500

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