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Article

An estrogen receptor-negative breast cancer subset characterized by a hormonally regulated transcriptional program and response to androgen.

Oncogene - 29 Jun 2006

Doane A S, Danso M, Lal P, Donaton M, Zhang L, Hudis C, Gerald W L

Abstract excerpt

Little is known of the underlying biology of estrogen receptor-negative, progesterone receptor-negative (ER(-)/PR(-)) breast cancer (BC), and few targeted therapies are available. Clinical heterogeneity of ER(-)/PR(-) tumors suggests that molecular subsets exist. We performed genome-wide expression analysis of 99 primary BC samples and eight BC cell lines in an effort to reveal distinct subsets, provide insight...

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Share to Androgens
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, Estrogen

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Source

Identifiers

PMID: 16491124
DOI: 10.1038/sj.onc.1209415

Genes

ALCAM
APOD
FOXA1
NAT1
SPDEF
TFF3
XBP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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