Subtype-specific alternative splicing events in breast cancer identified by large-scale data analysis.

doi:10.1038/s41598-024-65035-y

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Article

Subtype-specific alternative splicing events in breast cancer identified by large-scale data analysis.

Scientific reports - 19 Jun 2024

Deguchi Yui, Kikutake Chie, Suyama Mikita

Abstract excerpt

Genome analysis in cancer has focused mainly on elucidating the function and regulatory mechanisms of genes that exhibit differential expression or mutation in cancer samples compared to normal samples. Recently, transcriptome analysis revealed that abnormal splicing events in cancer samples could contribute to cancer pathogenesis. Moreover, splicing variants in cancer reportedly generate diverse cancer antigens....

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PMID: 38898123
DOI: 10.1038/s41598-024-65035-y
PMCID: PMC11187070

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