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Article

Genetic polymorphisms and the development of invasive bacterial infections in children.

International journal of immunopathology and pharmacology - 1 Mar 2016

Esposito Susanna, Bosis Samantha, Orenti Annalisa, Spena Silvia, Montinaro Valentina, Bianchini Sonia, Zampiero Alberto, Principi Nicola

Abstract excerpt

To evaluate the associations between single nucleotide polymorphisms (SNPs) of factors involved in the development of invasive bacterial disease (IBD) in children, 47 SNPs of 18 candidate genes were analysed in 49 children with IBD and 100 controls. The G/T genotype of TLR2 rs2149356 and the C genotype of LTA rs2229094 were associated with significantly reduced risk of developing IBD (P=0.04 and P=0.05,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 26684632
DOI: 10.1177/0394632015622961
PMCID: PMC5806737

Genes

LTA
TLR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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