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Article

Genetic and environmental factors significant for the presentation and development of inflammatory bowel disease.

European journal of gastroenterology & hepatology - 1 Aug 2017

Dragasevic Sanja, Stankovic Biljana, Milosavljevic Tomica, Sokic-Milutinovic Aleksandra, Lukic Snezana, Alempijevic Tamara, Zukic Branka, Kotur Nikola, Nikcevic Gordana, Pavlovic Sonja, Popovic Dragan

Abstract excerpt

OBJECTIVES: The aim of the study was to evaluate associations between inflammatory bowel disease (IBD) presentation and variants in NOD2, TLR4, TNF-α, IL-6, IL-1β, and IL-RN genes in order to identify possible environmental factors that may affect IBD occurrence, investigate potential predictors for surgical treatment of IBD, and correlate the presence of granulomas in biopsy specimens with clinical...

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Identifiers

PMID: 28452812
DOI: 10.1097/MEG.0000000000000877

Genes

TLR4
NOD2
TNF

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