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Article

Genetic risk factors for serious infections in inflammatory bowel diseases.

Scandinavian journal of gastroenterology - 1 May 2017

Sasidharan Saranya, Yajnik Vijay, Khalili Hamed, Garber John, Xavier Ramnik, Ananthakrishnan Ashwin N

Abstract excerpt

INTRODUCTION: Immunosuppression, the cornerstone of management of Crohn's disease (CD) and ulcerative colitis (UC) (inflammatory bowel diseases; IBD) is associated with an increased risk of serious infections that is inadequately predicted by clinical risk factors. The role of genetics in determining susceptibility to infections is unknown. METHODS: From a prospective-consented patient registry, we identified IBD...

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Identifiers

PMID: 28162010
DOI: 10.1080/00365521.2017.1286381
PMCID: PMC5642969

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