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Article

Promoter SNPs rs116896264 and rs73933062 form a distinct haplotype and are associated with galectin-4 overexpression in colorectal cancer.

Mutagenesis - 1 Jul 2016

Helwa Reham, Ramadan Mohamed, Abdel-Wahab Abdel-Hady A, Knappskog Stian, Bauer Andrea S

Abstract excerpt

Galectin-4 is a member of the galectin family which consists of 15 galactoside-binding proteins. Previously, galectin-4 has been shown to have a role in cancer progression and metastasis and it is found upregulated in many solid tumours, including colorectal cancer (CRC). Recently, the role in the metastatic process was suggested to be via promoting cancer cells to adhere to blood vascular endothelium. In the...

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Topics

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Share to Cell Line, Tumor
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

Share to Genetic Predisposition to Disease

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Share to Polymorphism, Single Nucleotide

Share to Promoter Regions, Genetic

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Source

Identifiers

PMID: 26681582
DOI: 10.1093/mutage/gev086

Genes

LGALS4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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