Article
Association between genetic variants in the promoter region of a novel antisense long noncoding RNA RP11-392P7.6 and colorectal cancer risk.
Environmental and molecular mutagenesis - 1 Jul 2017
Jin Mingjuan, Gu Simeng, Ye Ding, Li Yingjun, Jing Fangyuan, Li Qilong, Chen Kun
Abstract excerpt
There is a widespread occurrence of antisense transcripts' regulation on cancer-related genes in cancer biology. RP11-392P7.6 is antisense to the coding region of cancer-related gene GPRC5D, which has been found recently. The aim of this study was to investigate the associations of tagSNPs in the promoter region of RP11-392P7.6 with the risk of colorectal cancer. We conducted a two-stage case-control study, with...
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