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Article

Association of gene and protein expression and genetic polymorphism of CC chemokine ligand 4 in colorectal cancer.

World journal of gastroenterology - 14 Aug 2021

Shamoun Levar, Landerholm Kalle, Balboa Ramilo Amanda, Andersson Roland E, Dimberg Jan, Wågsäter Dick

Abstract excerpt

BACKGROUND: Leukocytes, such as T cells and macrophages, play an important role in tumorigenesis. CC chemokine ligand (CCL) 4, which is produced by lymphocytes and macrophages, has been found to be expressed in the mucosa of the gastrointestinal tract and is a potent chemoattractant for various leukocytes. AIM: To examine CCL4 expression and its genetic polymorphism rs10491121 in patients with colorectal cancer...

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Identifiers

PMID: 34497436
DOI: 10.3748/wjg.v27.i30.5076
PMCID: PMC8384737

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