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Article

CD44 Genotypes Are Associated with Susceptibility and Tumor Characteristics in Colorectal Cancer Patients.

The Tohoku journal of experimental medicine - 1 Feb 2020

Márquez-González Rosa María, Saucedo-Sariñana Anilú Margarita, Barros-Núñez Patricio, Gallegos-Arreola Martha Patricia, Pineda-Razo Tomás Daniel, Marin-Contreras María Eugenia, Flores-Martínez Silvia Esperanza, Sánchez-Corona José, Rosales-Reynoso Mónica Alejandra

Abstract excerpt

Colorectal cancer is the third cause of cancer and the second leading cause of death worldwide. The CD44 gene plays a key role in malignant processes, including growth, survival, epithelial to mesenchymal transition and metastasis. It is also known that some variants as rs187116 (c.67+4883G>A) and rs7116432 (c.2024+779A>G) can modulate the function of the CD44 gene and malignant transformation in several...

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PMID: 32115493
DOI: 10.1620/tjem.250.109

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