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Novel Screening Method for Anti-Colon Cancer Drugs Using Two Sensor Cell Lines with Human β4-Galactosyltransferase 4 Gene Promoters

2018-06-12

Abstract excerpt

The increased expression of β4-galactosyltransferase (β4GalT) 4 was closely associated with poor prognosis of colon cancer. Recently, we showed that the expression of the β4GalT4 gene is regulated by the 0.17 kb core promoter region containing one binding site for Specificity protein 1 (Sp1). To develop a novel screening method for anti-colon cancer drugs, two sensor cell lines having the luciferase...

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Literature Corpus work
ed7ae378-2fad-5b75-a640-9fa2f6e3ff95
DOI
10.20944/preprints201806.0192.v1
Open publication

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Novel Screening Method for Anti-Colon Cancer Drugs Using Two Sensor Cell Lines with Human β4-Galactosyltransferase 4 Gene PromotersDOI 10.20944/preprints201806.0192.v1
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