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Article

Genetic association and functional implications of TLR4 rs1927914 polymorphism on colon cancer risk.

BMC cancer - 18 Jul 2024

Li Ang, Gao Hui, Wu Hongjiao, Xie Yuning, Jia Zhenxian, Yang Zhenbang, Zhang Zhi, Zhang Xuemei

Abstract excerpt

BACKGROUND: Colon cancer remains a major health concern worldwide, with genetic factors playing a crucial role in its development. Toll-like receptors (TLRs) has been implicated in various cancers, but their role in colon cancer is not well understood. This study aims to identify functional polymorphisms in the promoter and 3'UTR regions of TLRs and evaluate their association with colon cancer susceptibility....

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Identifiers

PMID: 39026223
DOI: 10.1186/s12885-024-12604-z
PMCID: PMC11256370

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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