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Article

GALNT14: An Emerging Marker Capable of Predicting Therapeutic Outcomes in Multiple Cancers.

International journal of molecular sciences - 21 Feb 2020

Lin Wey-Ran, Yeh Chau-Ting

Abstract excerpt

Members of the polypeptide N-acetylgalactosaminyltransferase (GALNT) family function as the initiating enzymes that catalyze mucin-type O-glycosylation of proteins, and their dysregulated expression can alter cancer cell behaviors such as de novo occurrence, proliferation, migration, metastasis, and drug resistance. Recent studies have demonstrated that one of the family's members, GALNT14, is aberrantly...

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PMID: 32098271
DOI: 10.3390/ijms21041491
PMCID: PMC7073045

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