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Article

Genetic variants in C-type lectin genes are associated with colorectal cancer susceptibility and clinical outcome.

International journal of cancer - 15 Nov 2013

Lu Shun, Bevier Melanie, Huhn Stefanie, Sainz Juan, Lascorz Jesus, Pardini Barbara, Naccarati Alessio, Vodickova Ludmila, Novotny Jan, Hemminki Kari, Vodicka Pavel, Försti Asta

Abstract excerpt

Inflammatory responses play a vital role at different stages of colorectal carcinogenesis. C-type lectins mediate inflammatory/immune responses and participate in immune escape of pathogens and tumors. Our study aimed to evaluate the correlation between polymorphisms in three C-type lectin genes, CD209, MBL2 and REG4, and colorectal cancer (CRC) risk and clinical outcome. We genotyped 15 potentially functional...

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Source

Identifiers

PMID: 23650115
DOI: 10.1002/ijc.28251

Genes

REG4
MBL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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