Article
Genetic Polymorphisms in XRCC1, CD3EAP, PPP1R13L, XPB, XPC, and XPF and the Risk of Chronic Benzene Poisoning in a Chinese Occupational Population.
PloS one - 1 Jan 2015
Xue Ping, Gao Lin, Xiao Sha, Zhang Guopei, Xiao Mingyang, Zhang Qianye, Zheng Xiao, Cai Yuan, Jin Cuihong, Yang Jinghua, Wu Shengwen, Lu Xiaobo
Abstract excerpt
OBJECTIVES: Individual variations in the capacity of DNA repair machinery to relieve benzene-induced DNA damage may be the key to developing chronic benzene poisoning (CBP), an increasingly prevalent occupational disease in China. ERCC1 (Excision repair cross complementation group 1) is located on chromosome 19q13.2-3 and participates in the crucial steps of Nucleotide Excision Repair (NER); moreover, we...
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