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Article

Association of genetic polymorphisms in GADD45A, MDM2, and p14 ARF with the risk of chronic benzene poisoning in a Chinese occupational population.

Toxicology and applied pharmacology - 1 Oct 2009

Sun Pin, Zhang Zhongbin, Wan Junxiang, Zhao Naiqing, Jin Xipeng, Xia Zhaolin

Abstract excerpt

Benzene reactive metabolites can lead to DNA damage and trigger the p53-dependent defense responses to maintain genomic stability. We hypothesized that the p53-dependent genes may play a role in the development of chronic benzene poisoning (CBP). In a case-control study of 303 patients with benzene poisoning and 295 workers occupationally exposed to benzene in south China, we investigated associations between the...

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Source

Identifiers

PMID: 19596022
DOI: 10.1016/j.taap.2009.07.003

Genes

MDM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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