Article
Breast Cancer Risk Prediction Using Clinical Models and 77 Independent Risk-Associated SNPs for Women Aged Under 50 Years: Australian Breast Cancer Family Registry.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Feb 2016
Dite Gillian S, MacInnis Robert J, Bickerstaffe Adrian, Dowty James G, Allman Richard, Apicella Carmel, Milne Roger L, Tsimiklis Helen, Phillips Kelly-Anne, Giles Graham G, Terry Mary Beth, Southey Melissa C, Hopper John L
Abstract excerpt
BACKGROUND: The extent to which clinical breast cancer risk prediction models can be improved by including information on known susceptibility SNPs is not known. METHODS: Using 750 cases and 405 controls from the population-based Australian Breast Cancer Family Registry who were younger than 50 years at diagnosis and recruitment, respectively, Caucasian and not BRCA1 or BRCA2 mutation carriers, we derived...
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