Article
Using Breast Cancer Risk Associated Polymorphisms to Identify Women for Breast Cancer Chemoprevention.
PloS one - 1 Jan 2017
Ziv Elad, Tice Jeffrey A, Sprague Brian, Vachon Celine M, Cummings Steven R, Kerlikowske Karla
Abstract excerpt
BACKGROUND: Breast cancer can be prevented with selective estrogen receptor modifiers (SERMs) and aromatase inhibitors (AIs). The US Preventive Services Task Force recommends that women with a 5-year breast cancer risk ≥3% consider chemoprevention for breast cancer. More than 70 single nucleotide polymorphisms (SNPs) have been associated with breast cancer. We sought to determine how to best integrate risk...
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