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Article

Genome-Wide Association Studies in Drug-Induced Liver Injury: Step Change in Understanding the Pathogenesis.

Seminars in liver disease - 1 Nov 2015

Aithal Guruprasad P, Grove Jane I

Abstract excerpt

Hepatotoxicity constrains drug development and accounts for a substantial burden on health services. Genome-wide association studies (GWASs) have investigated potential genetic factors that explain interindividual variations in response to medications leading to drug-induced liver injury (DILI). Although the proportion of GWASs investigating DILI is very small, those that have focused on this area have identified...

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Identifiers

PMID: 26676816
DOI: 10.1055/s-0035-1567829

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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