Article
Drug-induced liver injury: a safety review.
Expert opinion on drug safety - 1 Aug 2018
García-Cortés Miren, Ortega-Alonso Aida, Lucena M Isabel, Andrade Raúl J
Abstract excerpt
INTRODUCTION: Idiosyncratic drug-induced liver injury (DILI) remains one of the most important causes of drug attrition both in the early phases of clinical drug development and in the postmarketing scenario. This is because, in spite of emerging data on genetic susceptibility variants associated to the risk of hepatotoxicity, the precise identification of the individual who will develop DILI when exposed to a...
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