Article
Genetic and Epigenetic Basis of Drug-Induced Liver Injury.
Seminars in liver disease - 1 May 2023
Singh Snigdha, Kumar P V S N Kiran, Kumar J Pradeep, Tomo Sojit, Yadav Dharamveer, Sharma Praveen, Rao Mahadev, Banerjee Mithu
Abstract excerpt
Drug-induced liver injury (DILI) is a rare but severe adverse drug reaction seen in pharmacotherapy and a major cause of postmarketing drug withdrawals. Advances in genome-wide studies indicate that genetic and epigenetic diversity can lead to inter-individual differences in drug response and toxicity. It is necessary to identify how the genetic variations, in the presence of environmental factors, can contribute...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.