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Article

Pharmacogenetics of drug‐induced liver injury†

19 Apr 2010

Abstract excerpt

Recent progress in research on drug-induced liver injury (DILI) has been determined by key developments in two areas. First, new technologies allow the identification of genetic risk factors with improved sensitivity, specificity, and efficiency. Second, new mechanistic concepts of DILI emphasize the importance of unspecific "downstream" events following drug-specific initial "upstream" hepatocyte injury and of...

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PMID: 20607838
DOI: 10.1002/hep.23720

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