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Article

Genetic basis of drug-induced liver injury: present and future.

Seminars in liver disease - 1 May 2014

Urban Thomas J, Daly Ann K, Aithal Guruprasad P

Abstract excerpt

There is considerable evidence that susceptibility to idiosyncratic drug-induced liver injury (DILI) is genetically determined. Though genetic associations with DILI have been reported since the 1980s, the development of genome-wide association studies has enabled genetic risk factors for DILI, in common with other diseases, to be detected and confirmed more confidently. Human leukocyte antigen (HLA) genotype has...

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Share to ATP-Binding Cassette Transporters
Share to Chemical and Drug Induced Liver Injury

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P-450 Enzyme System

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Source

Identifiers

PMID: 24879978
DOI: 10.1055/s-0034-1375954

Genes

NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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