Article
Oxidative phosphorylation and lacunar stroke: Genome-wide enrichment analysis of common variants.
Neurology - 12 Jan 2016
Traylor Matthew, Anderson Christopher D, Hurford Robert, Bevan Steve, Markus Hugh S
Abstract excerpt
OBJECTIVE: We investigated whether oxidative phosphorylation (OXPHOS) abnormalities were associated with lacunar stroke, hypothesizing that these would be more strongly associated in patients with multiple lacunar infarcts and leukoaraiosis (LA). METHODS: In 1,012 MRI-confirmed lacunar stroke cases and 964 age-matched controls recruited from general practice surgeries, we investigated associations between common...
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