Article
Common variants within oxidative phosphorylation genes influence risk of ischemic stroke and intracerebral hemorrhage.
Stroke - 1 Mar 2013
Anderson Christopher D, Biffi Alessandro, Nalls Michael A, Devan William J, Schwab Kristin, Ayres Alison M, Valant Valerie, Ross Owen A, Rost Natalia S, Saxena Richa, Viswanathan Anand, Worrall Bradford B, Brott Thomas G, Goldstein Joshua N, Brown Devin, Broderick Joseph P, Norrving Bo, Greenberg Steven M, Silliman Scott L, Hansen Björn M, Tirschwell David L, Lindgren Arne, Slowik Agnieszka, Schmidt Reinhold, Selim Magdy, Roquer Jaume, Montaner Joan, Singleton Andrew B, Kidwell Chelsea S, Woo Daniel, Furie Karen L, Meschia James F, Rosand Jonathan
Abstract excerpt
BACKGROUND AND PURPOSE: Previous studies demonstrated association between mitochondrial DNA variants and ischemic stroke (IS). We investigated whether variants within a larger set of oxidative phosphorylation (OXPHOS) genes encoded by both autosomal and mitochondrial DNA were associated with risk of IS and, based on our results, extended our investigation to intracerebral hemorrhage (ICH). METHODS: This...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
