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Article

Mechanisms and treatment of ischaemic stroke--insights from genetic associations.

Nature reviews. Neurology - 1 Dec 2014

Markus Hugh S, Bevan Steve

Abstract excerpt

The precise pathophysiology of ischaemic stroke is unclear, and a greater understanding of the different mechanisms that underlie large-artery, cardioembolic and lacunar ischaemic stroke subtypes would enable the development of more-effective, subtype-specific therapies. Genome-wide association studies (GWASs) are identifying novel genetic variants that associate with the risk of stroke. These associations...

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PMID: 25348005
DOI: 10.1038/nrneurol.2014.196

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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