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Article

Genetic variation of oxidative phosphorylation genes in stroke and Alzheimer's disease.

Neurobiology of aging - 1 Aug 2014

Biffi Alessandro, Sabuncu Mert R, Desikan Rahul S, Schmansky Nick, Salat David H, Rosand Jonathan, Anderson Christopher D

Abstract excerpt

Previous research implicates alterations in oxidative phosphorylation (OXPHOS) in the development of Alzheimer's disease (AD). We sought to test whether genetic variants within OXPHOS genes increase the risk of AD. We first used gene-set enrichment analysis to identify associations, and then applied a previously replicated stroke genetic risk score to determine if OXPHOS genetic overlap exists between stroke and...

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Identifiers

PMID: 24650791
DOI: 10.1016/j.neurobiolaging.2014.01.141
PMCID: PMC4329419

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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