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Article

Protein phosphatase 2A (PP2A) activation promotes axonal growth and recovery in the CNS.

Journal of the neurological sciences - 15 Dec 2015

Cheng Peng, Chen Kun, Yu Wei, Gao Shutao, Hu Shunze, Sun Xuying, Huang Hui

Abstract excerpt

Current treatments to restore neurological deficits caused by axonal disconnection following central nervous system (CNS) injury are extremely limited. Protein phosphatase 2A (PP2A), one of the main serine-threonine phosphatases in mammalian cells, dephosphorylates collapsin response mediator protein-2 (CRMP2) in the developing CNS. In our study, we found that the major CNS inhibiting substrates, including...

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Identifiers

PMID: 26671085
DOI: 10.1016/j.jns.2015.10.025

Genes

EGFR
DES
EGF
MAG

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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