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Article

Kinase/phosphatase overexpression reveals pathways regulating hippocampal neuron morphology.

Molecular systems biology - 1 Jul 2010

Buchser William J, Slepak Tatiana I, Gutierrez-Arenas Omar, Bixby John L, Lemmon Vance P

Abstract excerpt

Development and regeneration of the nervous system requires the precise formation of axons and dendrites. Kinases and phosphatases are pervasive regulators of cellular function and have been implicated in controlling axodendritic development and regeneration. We undertook a gain-of-function analysis to determine the functions of kinases and phosphatases in the regulation of neuron morphology. Over 300 kinases and...

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Source

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Identifiers

PMID: 20664637
DOI: 10.1038/msb.2010.52
PMCID: PMC2925531

Genes

CHKA
PKN2
PPEF2
SMPD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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