Article
Mutation Screening of 1,237 Cancer Genes across Six Model Cell Lines of Basal-Like Breast Cancer.
PloS one - 1 Jan 2015
Olsson Eleonor, Winter Christof, George Anthony, Chen Yilun, Törngren Therese, Bendahl Pär-Ola, Borg Åke, Gruvberger-Saal Sofia K, Saal Lao H
Abstract excerpt
Basal-like breast cancer is an aggressive subtype generally characterized as poor prognosis and lacking the expression of the three most important clinical biomarkers, estrogen receptor, progesterone receptor, and HER2. Cell lines serve as useful model systems to study cancer biology in vitro and in vivo. We performed mutational profiling of six basal-like breast cancer cell lines (HCC38, HCC1143, HCC1187,...
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