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Article

Targeted sequencing reveals the somatic mutation landscape in a Swedish breast cancer cohort.

Scientific reports - 9 Nov 2020

Mathioudaki Argyri, Ljungström Viktor, Melin Malin, Arendt Maja Louise, Nordin Jessika, Karlsson Åsa, Murén Eva, Saksena Pushpa, Meadows Jennifer R S, Marinescu Voichita D, Sjöblom Tobias, Lindblad-Toh Kerstin

Abstract excerpt

Breast cancer (BC) is a genetically heterogeneous disease with high prevalence in Northern Europe. However, there has been no detailed investigation into the Scandinavian somatic landscape. Here, in a homogeneous Swedish cohort, we describe the somatic events underlying BC, leveraging a targeted next-generation sequencing approach. We designed a 20.5 Mb array targeting coding and regulatory regions of genes with...

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Identifiers

PMID: 33168853
DOI: 10.1038/s41598-020-74580-1
PMCID: PMC7653953

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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