Article
Genome-wide mutational analyses of breast and colorectal cancers.
Discovery medicine - 1 Feb 2007
Lin Jimmy, Sjöblom Tobias
Abstract excerpt
With the human genome sequence at hand, it is now possible to sequence coding regions of cancer cell genomes to identify the mutated genes that drive tumor formation. The clinical importance of breast and colorectal cancer, together causing 14% of yearly cancer deaths, make these two tumor types suitable initial candidates for cancer genome sequencing. We recently surveyed more than half of the known human genes...
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