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Article

Mutations in EGFR, BRAF and RAS are rare in triple-negative and basal-like breast cancers from Caucasian women.

Breast cancer research and treatment - 1 Jan 2014

Tilch E, Seidens T, Cocciardi S, Reid L E, Byrne D, Simpson P T, Vargas A C, Cummings M C, Fox S B, Lakhani S R, Chenevix Trench G

Abstract excerpt

Basal-like and triple-negative breast cancers usually display a high level of genomic instability and often carry TP53 mutations. Mutations in EGFR have been reported in about 10 % triple-negative tumours from Chinese women, and there is some evidence that triple-negative and basal-like tumours might carry additional mutations against which targeted therapies are available. We, therefore, sought to determine the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24318467
DOI: 10.1007/s10549-013-2798-1

Genes

EGFR
MET
AKT1
BRAF
KRAS
NRAS

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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