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Article

KCNE3 acts by promoting voltage sensor activation in KCNQ1.

Proceedings of the National Academy of Sciences of the United States of America - 29 Dec 2015

Barro-Soria Rene, Perez Marta E, Larsson H Peter

Abstract excerpt

KCNE β-subunits assemble with and modulate the properties of voltage-gated K(+) channels. In the colon, stomach, and kidney, KCNE3 coassembles with the α-subunit KCNQ1 to form K(+) channels important for K(+) and Cl(-) secretion that appear to be voltage-independent. How KCNE3 subunits turn voltage-gated KCNQ1 channels into apparent voltage-independent KCNQ1/KCNE3 channels is not completely understood. Different...

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Source

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Identifiers

PMID: 26668384
DOI: 10.1073/pnas.1516238112
PMCID: PMC4703023

Genes

KCNQ1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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