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Article

Proteomic analysis of physiological versus pathological cardiac remodeling in animal models expressing mutations in myosin essential light chains.

Journal of muscle research and cell motility - 1 Dec 2015

Gomes Aldrin V, Kazmierczak Katarzyna, Cheah Jenice X, Gilda Jennifer E, Yuan Chen-Ching, Zhou Zhiqun, Szczesna-Cordary Danuta

Abstract excerpt

In this study we aimed to provide an in-depth proteomic analysis of differentially expressed proteins in the hearts of transgenic mouse models of pathological and physiological cardiac hypertrophy using tandem mass tag labeling and liquid chromatography tandem mass spectrometry. The Δ43 mouse model, expressing the 43-amino-acid N-terminally truncated myosin essential light chain (ELC) served as a tool to study...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26668058
DOI: 10.1007/s10974-015-9434-0
PMCID: PMC4847725

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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