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Article

The IL17F and IL17RA Genetic Variants Increase Risk of Cerebral Malaria in Two African Populations.

Infection and immunity - 1 Feb 2016

Marquet Sandrine, Conte Ianina, Poudiougou Belco, Argiro Laurent, Cabantous Sandrine, Dessein Hélia, Burté Florence, Oumar Aboubacar A, Brown Biobele J, Traore Abdoualye, Afolabi Nathaniel K, Barry Abdoulaye, Omokhodion Samuel, Ndoumbe Ursule Ewanda, Shokunbi Wuraola A, Sodeinde Olugbemiro, Doumbo Ogobara, Fernandez-Reyes Delmiro, Dessein Alain J

Abstract excerpt

Cerebral malaria (CM) is a neurological complication of infection with Plasmodium falciparum that is partly caused by cytokine-mediated inflammation. It is not known whether interleukin-17 (IL-17) cytokines, which regulate inflammation, control the development of CM. To evaluate the involvement of IL-17 cytokines in CM, we analyzed 46 common polymorphisms in IL17A, IL17F, and IL17RA (which encodes the common...

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Identifiers

PMID: 26667835
DOI: 10.1128/IAI.00671-15
PMCID: PMC4730560

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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