Article
Gene polymorphisms of IL-17A and bacterial meningitis in Angolan children.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Mar 2024
Teräsjärvi Johanna, Tenhu Elina, Cruzeiro Manuel Leite, Savonius Okko, Rugemalira Emilie, He Qiushui, Pelkonen Tuula
Abstract excerpt
Interleukin (IL)-17 A plays a crucial role in protecting hosts from invading bacterial pathogens. In this study, we investigated if single nucleotide polymorphisms (SNPs) in IL-17A are associated with susceptibility and outcome of bacterial meningitis (BM) in Angolan children. The study sample comprised 241 confirmed BM patients and 265 controls, which were matched for age and ethnicity. Three IL-17A SNPs -...
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